SELPLG Antikörper

Produktnummer ABIN6297562

Dieser Maus Monoklonal Antikörper erkennt spezifisch SELPLG in FACS, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SELPLG Antikörper (ABIN6297562)

Target: SELPLG (Selectin P Ligand (SELPLG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SELPLG Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-SELPLG Antikörper

Verwendungszweck: Mouse anti-Human CD162 Antibody / P selectin glycoprotein ligand 1 / PSGL-1 [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.

Immunogen: Recombinant human PSGL-1 protein was used as the immunogen for the PSGL-1 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: P-selectin glycoprotein ligand 1

Hintergrund:

Target Description: P selectin glycoprotein ligand 1 (PSGL-1), also called CD162 glycoprotein, functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Gene Symbol: SELPLG

Gen-ID: 6404

UniProt: Q14242